Our new Apparent+ tissue clearing technique is the sole approach that delipidates samples without transform in morphology and with negligible impact on structural integrity.
Megatome is actually a vibrating microtome intended to part a wide range of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With higher blade vibrating frequency and minimized blade deflection, Megatome enables large-throughput tissue sectioning with uniform floor profile, together with small tissue destruction and knowledge loss.
Ask for a quotation or demo Uniformly portion significant tissues & sample arrays Megatome is the only real microtome that can section samples as big as intact nonhuman primate and human organs, making it invaluable for fields like neuropathology.
Megatome is suitable for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and contains a exclusive deflection Management system.
SE works by using a rotational electrical discipline to disperse very electromobile molecules (like antibodies or surfactant micelles) throughout a porous sample without harming electrically billed constructions inside the tissue. This enables 2-four working day clearing of intact organs,
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It’s time and energy to improve your microtome to Megatome. With exact large-frequency slicing for an unmatched range of sample measurements and types – from organoids and megatomi.com tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various applications.
Entirely delipidate whole mouse brains or comparably sized samples in just one working day with SmartBatch+, or in one 7 days with our passive clearing kit.
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Protect avoids the variability of hydrogel embedding and the knowledge reduction from PFA preservation, guarding specimens for various rounds of processing.
Leverage the Clear+ tissue clearing process, in conjunction with eFLASH and patented stochastic electrotransport technologies, to promptly crystal clear and label entire organs. Key highlights and capabilities contain:
Our novel Defend tissue preservation method varieties intramolecular bonds applying polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.